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Description

Clinical safety and efficacy of allogenic human adipose mesenchymal stromal cells-derived exosomes in patients with mild to moderate Alzheimer's disease: a phase I/II clinical trial

Claudia Bregonzio, CCT CONICET Crdoba, Argentina

The caveat with topical DHEA administration is that it does not undergo first-pass metabolism through the liver (no liver passage - no sulfation), so although a subsequent increase in salivary and blood spot DHEA is observed, DHEA-S levels remain unchanged