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Methods: In the human study, 27 end stage liver disease patients (12 HCC and 15 CLD) were included

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( We use XPPAUT (Ermentrout, The reduced methionine cycle model We construct a reduced methionine cycle model by carefully excising the methionine cycle sub-network from the comprehensive Reed-Nijhout model (see Data Sheet 1 for full details)

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Biomed Res Int 2019:7602343 Wang D, Xiang DB, He YJ, Li ZP, Wu XH, Mou JH, Xiao HL, Zhang QH (2005) Effect of caffeic acid phenethyl ester on proliferation and apoptosis of colorectal cancer cells in vitro

The reaction mixture contained 50 mM sodium phosphate, 0.5 mM EDTA (pH 7.0), 1 mM GSH and 0.5 mM DHA in a total volume of 1 mL