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Wang CW, Miao YH, Chang YS

It has been reported that AGEs adversely affect several processes by two primary mechanisms: Directly through trapping and cross-linking of proteins, and indirectly by binding to specific receptors for AGE on the surface of various cells

DOSING SCHEDULE Initial dose escalation should take place in a clinical setting

Furthermore, 60 M QE could induce the poly (ADP-ribose) polymerase as a DNA repair enzyme cleavage in a time-dependent manner (Huang et al., 2013)

Whitaker, F

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