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Peptides occupy a central position in AD pathobiology: pathogenic species such as A oligomers and tau-derived fragments drive synaptic failure, mitochondrial dysfunction, and neuroinflammation, whereas several endogenous neuropeptides exert compensatory neuroprotective, trophic, or homeostatic effects

Among them, BPC-157 (Body Protection Compound-157) stands out for its remarkable ability to accelerate tissue repair, reduce inflammation, and protect vital organs

Ten-to-twelve-month-old beagle dogs weighing between 9.8 and 12.8 kg were purchased from YaDong Experimental Animal Research Centre, Nanjing, China

7 , eabl7482 (2022)

Dean BJ, et al