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10.3390/cancers12103005 277 NegroniA.ColantoniE.CucchiaraS.StronatiL

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This reduced response is often referred to as tachyphylaxis, where the body gradually adapts to the external hormone and makes it less effective with continued use

It is the most abundant molecule (endogenous antioxidant) with the lowest molecular weight

Moreover, a recent study suggested that BNN20, a C17-spiroepoxy derivative of DHEA, could function as a neuroprotective molecule to reduce inflammation by binding to the neurotrophin receptor (125)

The plate was shaken for 30 s and incubated for 10 min