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And this process is independent of other SGK1 target, the FOXO transcription factor DAF-16 and phase II ROS detoxification SKN-1/NFE2L2/NRF2 [62]

AMP kinase-mediated activation of the BH3-only protein Bim couples energy depletion to stress-induced apoptosis

In all cases, stage L4 worms were used at t = 0 for lifespan analyses and worms were transferred every 23 days to new agar plates

Low glutathione levels can lead to pigmentation, dark spots, and accelerate signs of aging like wrinkles

SIRT6, oxidative stress, and aging

PSCI affects a significant proportion of survivors, manifesting as deficits in memory, executive function, and attention that markedly diminish quality of life and functional independence