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(1992, Biochem J) demonstrated that IGF-1 and its variants including Long R3 IGF-1 are anabolic in dexamethasone-treated rats, confirming the utility of IGF-1 LR3 in models of catabolic states and muscle wasting where native IGF-1 activity is suppressed by glucocorticoid-driven IGFBP upregulation

It is useful to have a reference standard for measurements of reduction potentials just as in measurements of Gibbs free energy changes

Additionally, quercetin promoted DNA damage in NSCLC cells, as evidenced by upregulated -H2AX protein expression and increased occurrence of DNA fragmentation

USA 100: 358-363

Mol Psychiatry 26:45704582

doi: 10.1016/j.jchemneu.2020.101800 112