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In addition, the application of ice for 510 minutes before, 1535 minutes during, and 30 minutes after chemotherapy significantly reduces mucositis (Chaveli-Lopez 2016

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To better elucidate a potential mechanism that would explain our findings, single-cell RNA sequencing should be considered for future work

Lancet 381 , 117124 (2013)

The resulting prenylated intermediate, dimethylallyl-toluquinol, would then be cyclized to 5,8-dihydro-2,7-dimethylnaphthalene-1,4-diol, which would subsequently be aromatized to produce chimaphilin (Figure 2)

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