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BACKGROUND OF THE INVENTION The ubiquitous tripeptide L-glutathione (GSH) (gamma-glutamyl-cysteinyl-glycine), is a well-known biological antioxidant, and in fact is believed to be the primary intracellular antioxidant for higher organisms

A meta-analysis showed significant improvements in fasting blood glucose and insulin resistance with doses 2,000 mg daily for 12 weeks

Given potential hepatotoxicity, azathioprine is avoided in the setting of high bilirubin and acute liver failure

BMJ Open 9:e028536

Hepatology (2018) 67:32857

27 Cao et al found that changing the gut microbiota, specifically by lowering the production of TMA and TMAO, may help reduce acute lung injury caused by sepsis by blocking the nuclear factor-B signaling pathway