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For instance, convincing in vitro work indicates that homocysteine may cause a specific impairment of the binding capacity of annexin II for t-PA that may alter the endothelial-dependent fibrinolytic potential (Hajjar et al, 1998)

NF-kB signaling needs to be downregulated in order to maintain tissue homeostasis

This suggests that GSH levels are maintained at an innate level that is distinct between individuals

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Although no study directly investigating the effect of urolithin A on sleep outcomes was identified, our search found four preclinical studies that included outcomes relevant to sleep

We will also collect necessary data to evaluate target engagement in the CNS and disease-modifying effects in aMCI/early AD