l carnitine dietary sources Carnitine: the claims and why it may not work A Beginner's Guide to L-Carnitine

The safety and effectiveness of L-carnitine administration remain an issue for scientific investigation

Of the 223 enrolled participants, 95 (43%) were men, and 128 (57%) were women

2007;581(Pt 2):431444

Supplementation in high doses (over 1000 mg) relatively shortly before training appears to be advisable, as circulating L-carnitine - in contrast to muscle carnitine - presumably has a vascular-protective effect against oxidative damage in the microvascular area

However, the study did not include a control group, which limits the ability to attribute observed effects solely to L-carnitine supplementation

Fundam Clin Pharmacol