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Incubation of NFT with cell or tissue homogenates, microsomal preparations, or isolated mitochondria revealed one-electron reduction of NFT to yield an NFT radical anion ( NFT ) by flavoprotein-reductases such as xanthine oxidase, aldehyde dehydrogenase, thioredoxin reductase, cytochrome b 5 reductase, and cytochrome P450 reductase (CYPOR) (Miller et al

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Previous studies have shown that IGF-1 and IGF-1R are linked to both hypertrophy and atrophy in skeletal muscle through the PI3K/AKT signaling pathway, but their role in the pathogenesis of MTrPs remains unclear 22,23

Expected Results: Timeline and Benchmarks Setting realistic expectations requires understanding how each compound contributes over time