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GHK-Cu directly stimulates fibroblasts (the cells that produce collagen) to increased synthesis of: Type I collagen , the main structural protein of skin, tendons, ligaments (+70 % in the Maquart 1988 studies) Type III collagen , a more flexible type for regenerative tissues Elastin , the protein responsible for the elasticity of skin Decorin and glycosaminoglycans , hyaluronan, dermatan sulfate In the dermatological area this explains the anti-wrinkle effect of GHK-Cu, restoration of the skins collagen structure, which weakens with age

Cassandra Mackey, MD (Assistant Professor of Emergency Medicine, UMass Chan Medical School)

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DOI: 10.1016/j.euroneuro.2015.09.005 Note: All clinical citations relate to pharmaceutical research studies conducted under medical supervision in clinical trial settings

albicans was conducted for fuscotorunones A and B

Rational design of novel immunosuppressive drugs: Analogues of azathioprine lacking the 6-mercaptopurine substituent retain or have enhanced immunosuppressive effects