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The inhibition of bovine heart hexokinase by 2-deoxy-D-glucose-6-phosphate: characterization by 31 P NMR and metabolic implications

The evidence is insufficient, the side effect profile is disproportionate, and better-supported alternatives exist

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Specifically, B12 in animals is essential for carbohydrate, fat and protein metabolism, and the formation and regeneration of red blood cells, as well as the maintenance of the central nervous system