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Wang CX, Chen LH, Zhuang HB, Shi ZS, Chen ZC, Pan JP, et al

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While these responses are adaptive in the short term, prolonged exposure to high cortisol levels and chronic stress can lead to maladaptive outcomes such as immunosuppression, impaired growth, altered behaviour, and oxidative damage, leading to increased disease susceptibility and reduced performance [19, 83]

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Regulatory T cells infiltrate the tumor-induced tertiary lymphod structures and are associated with poor clinical outcome in NSCLC

10.1002/ddr.21936 141 PerazellaM