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Realistic Cd burdens appear to represent a serious threat to honey bees in terms of development and survival and larval stages to be especially susceptible to the toxic effects of Cd

It partially reversed stroke-induced intestinal barrier disruption and leakage, inflammation, dyslipidemia and oxidative stress, as well as the stroke-induced increase in pathogenic gut microbiota (e.g., Escherichia-Shigella , Enterococcus, Clostridium_innocuum_group ) and decrease in beneficial microbiota (e.g., Lachnospiraceae , unclassified__f__Lachnospiracea and Ruminococcus_torques_group )

Their expression was validated in bulk RNA-seq datasets

Calil et al., 2018

2.5 Immune microenvironment With the continuous study of tumor immunity, some researchers have proposed several immune subtypes of tumors based on the histological characteristics of tumors ( Figure 2 )

This approach revealed enrichment of the PPARA, a liver metabolic regulator, in BWS hepatocytes 31,57