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The initial outcome of the mitochondrial respiratory chain is the generation of O 2 , which is formed at numerous mitochondrial locations, encompassing NADH:ubiquinone oxidoreductase (complex I), succinate dehydrogenase (complex II), ubiquinol:cytochrome c oxidoreductase (complex III), and mitochondrial glycerol 3-phosphate dehydrogenase [15]

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Cell 40 359369 Brandon M, Baldi P and Wallace DC 2006 Mitochondrial mutations in cancer

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