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TLK286 clinical effects were investigated in the last decade in phase II and phase III trials for the treatment of drug-resistant ovarian cancer 112,113

IsoalloLCA is a bile acid metabolite, which can enhance mtROS production in CD4 + T cells

Primary PEMs Female 6- to 8-week-old mice (ICR or C57BL/6 J) were euthanized after 3 to 4 days of intraperitoneal injection of 2 ml of 4% sterile thioglycolate

17,99 In addition, ferroptosis inducers enhances the antitumor activity of radiation in selected xenograft tumor models, 100 suggesting that induction of ferroptosis may be an option to overcome radioresistance

These studies employ a method of exogenously introduced telomerase/bilirubin treatment on myocardial ischemia/infarction injury, resulting in a reduced cardiac muscle damage, possibly by modulating cell death

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