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Oleacein had the best binding affinity for LDLR, whereas luteolin had the best binding affinity for PCSK9 and ACLY

6 In NOX-independent NETosis, ROS are produced by mitochondria and are triggered by stimuli such as calcium ionophores or ultraviolet light

Biochem Pharmacol 37:47634774 Bartolone JB, Cohen SD, Khairallah EA (1989) Immunohistochemical localization of acetaminophen-bound liver proteins

Supplementary material The Supplementary Material for this article can be found online at: Abbreviations MEs, Metabolic enzyme-genes

These results suggest that inactivation of GSTA4 reduces proliferation by blocking PI3K/AKT and p38 MAPK signaling pathways and that activation of AKT and p38 pathways in HCT116 CRC cells occurs in a GSTA4-dependent manner