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Individual components of the apoptotic machinery involved in regulation of ER stress-mediated cell death include Bax, Bak, Bim, or PUMA (p53 upregulated modulator of apoptosis), as well as the transcription factor CHOP (C/EBP homologous protein)-dependent pathway [89]

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COA, HPLC/MS, salt form, and blend document review is treated as search context, not as a protocol or outcome claim

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metformin in children with NAFLD, showed that both improved hepatocellular ballooning and the NAFLD activity score (NAS), but neither vitamin E nor metformin decreased alanine aminotransferase (ALT) values or hepatic steatosis, inflammation, or fibrosis in NASH

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& Farokhzad, O

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QSAR classification models for predicting the activity of inhibitors of beta-secretase (BACE1) associated with Alzheimers disease

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