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It participates in the Keap1/Nrf2/ARE biological pathway the primary mechanism by which sulforaphane exerts its beneficial effects

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Scurvy also affects the skin, particularly causing excessive keratinization of hair follicles, bruising, bloody spots on the skin, and impaired wound healing (245, 246)

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These findings suggest that strategies aimed at mitigating ferroptosis, such as activating and upregulating the GPX4 pathway, may offer promising therapeutic avenues for ALS (Wang et al., 2022)