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Older adults also show inflammatory markers like IL-6 are often much higher than in young adults, and chronically elevated inflammation is associated with heart disease, diabetes, and cognitive decline

10.1016/j.nbd.2020.105162 222 RondinelliM.NovaraF.CalcaterraV.ZuffardiO.GenoveseS

These can include increased blood pressure and a fast or irregular heartbeat

doi: 10.1093/ACPROF:OSO/9780198717478.003.0003 38 Espinosa-DiezCMiguelVMennerichDKietzmannTSnchez-PrezPCadenasSet al

One study describes a novel probiotic organism that can directly produce interleukin-10 (IL-10) , an anti-inflammatory cytokine that promotes immune tolerance (de Moreno de Leblanc 2011

Despite the encouraging advances in therapeutic development, further research is urgently needed to establish more personalized and accessible treatment paradigms for MASLD in the near future [95]