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PLoS Genet 2 , e108 (2006)

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The data pooled from 7 fields of view across 2 cultures in one experiment

The study by Oehler and colleagues in 2002 (34) examined pathologic changes of the synovial membrane in patients with early-stage OA and identified four histological patterns of OA-associated synoviopathy: (i) synovial lining hyperplasia, (ii) sublining and capsular fibrosis, (iii) macromolecular cartilage and bone debris (detritus-rich), and (iv) inflammatory manifestations and stromal vascularization ( Figure 2 ) (3538)

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Acetyl-L-carnitine is the principal acylcarnitine ester [12]