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Additionally, the MMGBSA binding free energy of the GPX3-Diosgenin complex was -23.52 kcal/mol ( Supplementary Table 3 ), indicating good conformational stability and reliable binding affinity of the complex

Conversely, mice that received FMT from STS patients showed an increase in the infiltration of CD4 + FOXP3 + cells and bone marrow-derived suppressor cells in the tumor

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307 KEGG pathway enrichment analysis revealed that distinct metabolites are involved primarily in amino acid metabolism, including arginine and proline metabolism

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