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Trial participants had medical supervision, standardized doses, and specific titration schedules

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Figure 2 In the late 1990s Taisho Pharmaceuticals filed patent applications covering compounds that according to competitive experiments with radiolabeled [ 125 I]Ang IV exhibited high affinity to hippocampus membranes from guinea pig (Kobori et al., 1997

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Importantly, information regarding the indications, dosing, frequency, and duration of treatment remains unknown. Theres almost zero basically zero evidence in human trials, Spittler said