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Glutathione, a crucial endogenous antioxidant, has been proposed as a potential neuroprotective agent capable of mitigating MDMA-induced cerebral damage.Sixty adult male Wistar rats were randomly assigned to six experimental groups and administered oral treatments for 56 days: MDMA (5 mg/kg or 15 mg/kg), glutathione (15 mg/kg), or their combinations

A rapid rise in B12 levels was noted

Purine catabolism is an underappreciated, but important component of the homeostatic response of mitochondria to oxidant stress

Due to their instability, these compounds rapidly degrade into toxic end-products such as malondialdehyde (MDA) and 4-hydroxynonenal (4-HNE) [117, 118]

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Nanoparticles coated with Siglec-8 ligands are another potential strategy to target eosinophils in tissues