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461 Furthermore, certain genes may also impact changes in related pathways, leading to radiotherapy resistance

bioRxiv2024 September 26

45 if very lean) [11][12]

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Calcium (and calpains) also over-activate the protein kinase CDK5, which injures mitochondria by hyper-phosphorylating key components and also can cause postmitotic neurons to re-enter the cell cycle 108,216219

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