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During development of the myeloid lineage, GPX1 and GPX4 expression turns out to drastically increase, notably in human common myeloid progenitors (CMP), granulocytes-monocytes progenitors (GMP), megakaryocyte-erythroid progenitors (MEP) and in monocytes, while it remains very low in polymorphonuclear cells (PMN) (Fig

The Myh11-DreERT2Lgals3-Cre dual recombination system achieves highly specific tracing via independent Dre-loxP and Cre-loxP pathways, confirming that Lgals3 cells originate from in situ conversion of VSMCs rather than myeloid infiltration [231]

This lavage or mobilization procedure is called an arthrocentesis assisted joint manipulation

By comparing CD38-expressing T H subsets in dural meninges and Pps, we also showed that loss of controlling T regs might account for the expansion of T H 17 cells, providing further evidence that meningeal immunity resembles that of the gut 58,59

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