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RNAseq Reveals DEGs associated with antioxidant activity and disease-relevant phenotypes with SalA treatment RNA-seq was performed on 15 dae Drosophila , an age at which significant age-related and neurodegenerative phenotypes emerge in Drosophila models (Tan et al

Given that the Phase I clinical trial in IPF demonstrated a reduction of senescent cells and SASP within eleven days after a single treatment of D+Q, and improvements in physiological outcomes after 10 weeks (105), we reasoned that a three-month period would provide important feasibility, compliance and efficacy data, as well as potentially reveal other cognitive and biomarker effects useful for designing a larger study

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61 We also saw an upregulation of TNF- with our highest level of glutamine in aged tendons