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Frequent and heavy cannabis use can lead to addiction, specifically Cannabis Use Disorder, which research shows affects 3 in 10 users

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and Altria are more than cigarettes, the Big Three have taken more share of the discount segment and Altria could trip debt covenants

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It is critical to find the putative temporal contributors to the population-level decreases in smoking prevalence so we can maintain the downward trend, adjust regulations, if need be, and attain the Healthy People 2030 target of 6% current use of cigarettes among American adults 4