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GPx1 functions as a substrate for c-Abl- and Arg-mediated phosphorylations in Tyr-96, which induces its activity

We found that 76% of eQTLs detected in at least one stimulated condition were also found in naive cells

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448 Importantly, adalimumab can also be used in patients with poor response to etanercept (i.e., patients who did not reach PASI 50)

For instance, mutations outside the canonical RRDR in rpoB, like P280L and D595Y, also contribute to resistance, indicating a broader mutational landscape (Zeng et al., 2021)