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Epub 2005 Apr 26

For megaloblastic anaemia , one 500 microgram ampoule is given three times a week, and after about two months the dose is usually reduced to one ampoule every 1 to 3 months for maintenance

CHOIR: A randomized, prospective trial, 1432 patients with anemia due to CKD who were not undergoing dialysis and who had not previously received epoetin alfa therapy were randomized to epoetin alfa treatment targeting a maintenance hemoglobin concentration of either 13.5 g/dL or 11.3 g/dL

Knee arthroplasty was used as the severity indicator for OA development