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The second time that an ACO's benchmark is adjusted based on the ACO's regional service area expenditures, CMS calculates the regional adjustment using either the 50 percent of the difference between the average per capita amount of expenditures for the ACO's regional service area and the average per capita amount of the ACO's rebased historical benchmark if the ACO is determined to have lower spending than the ACO's regional service area ( 425.656(e)(2)(i))

J., Hegeds, L

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As shown in Figure 4, 40 volunteers received a dose of 30, 60, 150, or 300 mg genistein orally

For example, this should include time-of-day chronotherapeutic studies that examine whether exogenous melatonin is most beneficial to be given to patients in relation to endogenous rhythms

For example, FASN activity has been associated with HER2 marker, metastasis, relapse and chemoresistance [72, 150]