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Mol Cell Biochem 266:3756 Valko M, Rhodes CJ, Moncola J, Izakovic M, Mazura M (2006) Free radicals, metals and antioxidants in oxidative stress-induced cancer

However, there may be upregulation of succinate and aspartate (Zhou et al., 2018)

Cells were then incubated with or without cisplatin, etoposide (Cell Signaling Technologies, 2200S), doxorubicin (Sigma-Aldrich, D1515), staurosporin (Cell Signaling Technologies, 9953) or paclitaxel (Cell Signaling Technologies, 9807S) for an indicated period

These effects were associated with the inhibition of NF-B nuclear translocation and reduced phosphorylation of B and mitogen-activated protein kinases, including p38, extracellular signal-regulated kinases 1 and 2 (Erk 1/2), and c-Jun N-terminal kinase (282)

To investigate the requirement of ROS for cell death, we used ROS scavengers

Notably, the activity of SSAO in patients with diabetes is related to the risk factors of AS, such as obesity, total cholesterol, high blood pressure and blood sugar