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According to Foulds, the evidence that nicotine is harmful to the developing brain is of about the same quality as evidence on the impact of caffeine on young people

They've been linked to several health concerns, like making it easier to get dependent and making mental health issues worse

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Cancer Smoking is a leading cause of cancer, affecting many parts of the body

Likewise, in murine macrophages, the activated 7nAChR can mediate Jak2-STAT3 activation and then can induce the phosphorylation of STAT3, which subsequently downregulates pro-inflammatory cytokines (e.g., IL6, IL12, and TNF-) [133]

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