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Furthermore, PCYT1A knockdown induced the formation of larger LDs in FA-rich cultural medium (Fig

This alteration of FA metabolism regulators is a part of the so-called fetal reprogramming that is a well-known hallmark of HF [134] and is characterized by a switch of substrate preference of cardiomyocytes to carbohydrates, as is the case in the immature heart [135]

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But research consistently shows that neurological and metabolic dysfunction begins at levels below 400500 pg/mL in many individuals

These alternative uses are investigational and not established clinical indications

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