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We selectively reexpressed 2 nAChRs in VTA dopamine or VTA -amino-butyric acid (GABA) neurons in 2/ mice to double-dissociate the aversive and rewarding conditioned responses to nicotine in nondependent mice, revealing that 2 nAChRs on VTA dopamine neurons mediate nicotines conditioned aversive effects, while 2 nAChRs on VTA GABA neurons mediate the conditioned rewarding effects in place-conditioning paradigms

[16] Villafane G, Duran R, Massano J, Mestre T, Thobois S

More robust study designs include case-control

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[DOI] [PMC free article] [PubMed] [Google Scholar] 9.Know the risks: youth and e-cigarettes

Materials and Equipment: Potting soil Top soil Small ceramic flower pots Bean seeds Water smoker assembly small green house that you make using Plexiglas Results of Experiment (Observation): Experiments are often done in series