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As lo explic el Licenciado Carlos Alberto Cliento Pintos (M.N

Interestingly, receptors for G-CSF are expressed in neurons throughout the central nervous system and activation of those receptors (by G-CSF) stimulates neurogenesis and protects neurons from damage

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In both in vitro (L-02 hepatocyte cells) and in vivo (BALB/c mice) models, curcumin reduced isoniazid-induced hepatotoxicity by activating the SIRT1/PGC-1alpha/NRF1 pathway, decreasing oxidative stress and inflammation, and thereby attenuating hepatic damage

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In: Hoath SB, Maibach HI, eds