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Neuroinflammation: A Critical Factor in Neurodegenerative Disorders PMC Ablation of ferroptosis regulator glutathione peroxidase 4 in forebrain neurons promotes cognitive impairment and neurodegeneration ScienceDirect Inhibition of microglia Nox2 by metabolically activated apocynin. Download Scientific Diagram Ferroptosis is a type of cell death driven by uncontrolled peroxidation of membrane phospholipids. Glutathione peroxidase 4 (GPX4) is the main regulator of ferroptosis, but how it protects membranes is not well Frontiers Microglia and Astrocyte Function and Communication: What Do We Know in Humans? Microglial Functions Explained: Immunity, Inflammation & Neurodegeneration Assay Genie
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