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BMC Microbiol (2020) 20:18

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Following calibration, cells were loaded into the chambers at a density of 1.01.5 10 cells per chamber, the chambers were closed airtight, and cells were allowed to equilibrate

Thiostrepton-induced ferroptosis depends on the STAT3GPX4 signalling pathway Given that TST-induced ferroptosis activated the STAT3GPX4 signalling pathway in pancreatic cancer cells, we assumed that TST promotes ferroptosis by regulating STAT3-GPX4 signalling

and increased levels of Bax, caspase-3 and caspase-9, confirming that -hederin induces apoptosis via the mitochondrial pathway (Wang et al