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Pesticide use in agriculture and Parkinson's disease in the AGRICAN cohort study

(2018) found that there may be limited CNS penetration in oral administration compared to IV, as shown by increases in GSH/GSSG and catalase but not cerebral GSH levels

It has been found that IV supplementation with magnesium can dramatically increase serum levels compared to oral supplementation, and increase the amount that is able to enter into cells