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Yuen KCJ, Samson SL

The discovery of CYP51A1 dates back to the mid-1970s, when studies using radiolabeled lanosterol in yeast and rat liver microsomes demonstrated the release of [14 C] formic acid, enabling a straightforward assay of lanosterol 14-demethylase activity across species [10]

Moreover, CRC cells exhibit marked metabolic plasticity, in which FAO serves as a key mitochondrial mechanism for energy compensation [13, 14]

PLoS One 7(3):e33527 Kim J-E, Ryu HJ, Kang T-C (2013) Status epilepticus induces vasogenic edema via tumor necrosis factor-/ endothelin-1-mediated two different pathways [J]

Although Exos have entered clinical trials and shown beneficial effects in various diseases [235], trials specifically investigating MSC-Exos for ferroptosis remain limited in the literature and registered clinical trials

Tube formation assay Angiogenesis was assessed by tube formation assay