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Third, although the protective effect of ISO against H 2 O 2 -induced oxidative damage in HaCaT cells was investigated in the present study, further experiments and collaborative discussions should be held to identify the effect of ISO on H 2 O 2 -induced melanocytes, which would improve the development of ISO as a source of antioxidants and provide a theoretical basis for the targeted therapy of vitiligo

As natural plant metabolites, PCs hold considerable promise as a therapeutic option for T2DM, but their specific mechanisms and clinical applications demand further research

doi: 10.1016/j.jff.2023.105783 166 GohRCMaharajanMKGopinathDFangCM

Funding This research was supported by Scientific planning project of youth education in Shandong province Undergraduate Academic Project (23BSH251)

Identifier NCT06066515