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These compounds undergo activation to toxic metabolites by numerous reactions, including glucuronidation by UGTs, acetylation by NATs, sulfonation by SULTs, and conjugation with amino acids by aminoacyltRNAsynthetase

Second, due to the interdependent nature of the IPPS payment components, it is very difficult to precisely quantify the impact associated with each proposed change

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This approach aims for chemical cardioversion to restore normal rhythm, rather than adhering to a regular maintenance dose regimen (71)