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doi: 10.1038/s41571-020-0352-8 279 HuinenZRHuijbersEJMvan BeijnumJRNowak-SliwinskaPGriffioenAW

Optimization Therapy works best when its part of a system, not a shortcut

In response to cytokines and endotoxins, the vagus nerve signals the brainstem, affecting fever and sickness behavior, as well as appetite and mood (171174)