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Retinal NLRP3 is elevated in mild cognitive impairment and activated in AD dementia, evidenced by increased caspase-1, cleaved interleukin-1, and cleaved N-terminal gasdermin-D

Journal of Applied Social Psychology, 37 (8), 17261756

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At position fifteen, the amino acid histidine (His) is replaced with a modified amino acid called D-Phenylalanine (D-Phe)

the ability of serotonin to block ghrelins orexigenic effects (Currie et al., 2010)