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Inhibiting this pathway holds promise as a hopeful therapeutic approach for HCC (10)

In these cases, the primary goal is to remove the tumor along with a margin of healthy tissue and nearby lymph nodes through a procedure known as a colectomy

Arteriovenous access and hand pain: the distal hypoperfusion ischemic syndrome

As an alternative to conventional whole-cell approaches, proteomic studies to elucidate CDDP resistance have been performed on enriched subcellular compartments (e.g., nuclei, mitochondria), 258, 259, 260 purified components known to participate in CDDP-elicited signaling pathways (e.g., immobilized CDDP, Y-box binding protein 1), 149, 261 as well as on serum samples from cancer patients

Am J Pathol, 53: 769-789

Its a catastrophic point of failure that is, thankfully, entirely avoidable