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In 2016, researchers first designed phosphate and pyrophosphate-containing linkers coupled with the well-established, cathepsin B sensitive, Val-Cit-PABA moiety aiming to deliver glucocorticoids

doi: 10.3389/fphar.2021.766082 267

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Butyrate increases the expression of TLRs which are involved in antiviral mechanisms and may also inhibit SARS-CoV-2 replication by downregulating high-mobility group box protein-1 (HMGB1) expression (Li J