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A) Survival curves for a single-dose treatment or for treatments involving a fixed first dose followed, after 2.5 or 23 hours of incubation (at 37C), by a range of second doses

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Consistent Protocols Keep dosing standardized across different peptides

or saline 5.0 mL/kg i.p.) given at 5 min after isoprenaline, we assessed the early occlusion-like syndrome in the isoprenaline-treated rats as an early multi- Biomedicines 2022,10, 265 4 of 38 organ failure (brain, heart, lung, liver, kidney and gastrointestinal lesions), thrombosis, intracranial (superior sagittal sinus) hypertension, portal and caval hypertension, and aortal hypotension, full presentation