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Phytochelatins (PCs) are the most important heavy metal chelators in living organisms, and have a high affinity toward heavy metals (Chia et al

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In the event that the response in a subject is insufficient at such doses, even higher doses (or effective higher doses by a different, more localized delivery route) may be employed to the extent that patient tolerance permits

Most reported adverse events are local irritation or contact dermatitis, generally mild and self-limited

GSH Clinical Aspects - Health & Harm GSH Deficiency: Causes: Genetic defects (e.g., glutathione synthetase deficiency), oxidative stress, malnutrition (cysteine), toxins, chronic diseases (liver disease, HIV, diabetes)